...with great caution. I'm not kidding.
You've given us very little to go on, @Clarabelle1... Do you "let" out parts/rooms of your house now? Either way, you'd have to create a brand new listing...and it wouldn't carry over your "star" ratings of your previous room(s) rental, etc. Your host reviews would remain if someone cared to look them up in your profile, but reviews would also be blank as this is not the same property as the room(s) you may have rented within your home.
I would be *very* careful doing this if you've never rented out your entire home. ...and also needless to say I would ensure you turn off Instant Book on the entire home. You could have a nasty surprise when you return.
Just my 2 cents...
Jann