I think it's a bit of a strange question to ask, myself, altho I understand people can be apprehensive and fearful (city people of country places, small town folks of big cities).
Of course there are places that are generally safer than others. But you really can't assure someone that your area is safe, nor should they assume that anywhere is. There are random acts of violence that can occur anywhere, people need to take responsibility for their own safety. I'm not referring to locks on the doors, but things like walking home at 4 AM.
Because it's a 20 minute walk from my place into town, and some of my younger guests like to go to the bars and such, they'll ask me if it's safe to walk home after dark. What I tell them is that no one so far has had any problem, including my 35 year old daughter who lived here for awhile and stayed out late, but that of course I can't "guarantee" anything, and that they might feel more comfortable taking a taxi for the $6 it costs.
There are always these stories in the media about some tourists in Mexico who got robbed or murdered. The back story is usually that they were out at some bar, drinking til 2AM, hanging out with sketchy people, accepting an offer from some really friendly guy, a total stranger, to come back to their place where he could hook them up with some really good weed, or stumbling drunk down a dark alley. Things they would never do at home, but hey, "We're on vacation in paradise, chill out and parteeee!"