@Marcus366 You'd need a separate listing for each configuration. Airbnb doesn't have a "select number of rooms" feature to apply within a listing.
But there's not a huge market for groups requiring multiple bedrooms in a home shared with the host. Once you get to that price point, you're going to just book an Entire Home property for more privacy. So if it's legal for you to host multiple lodgers in your home (and you can organize it in such a way to minimize risk of Covid spread) you can list each unit separately as a Private Room, and create a 4th listing that is an Entire Home property.
Would I recommend this to a new host? Definitely not. Each new listing gets a temporary boost in search results for a couple weeks, which is your best lifeline in a time with low demand. So I'd suggest starting with one listing - ideally the best room you have to offer - and gradually building your profile as you're bolstered by (hopefully) positive reviews.