@Lise1051
I agree with @Mike-And-Jane0 . If you are not a live in host, there are so many things that could go wrong in that scenario. Think about cleaning issues, noise disturbance, security concerns. You would be trusting one set of guests not to upset the others and, not being there, it might sometimes be difficult to tell what actually happened. Are you ready to compensate a guest, for example, if they claim the other guest broke or stole something from them?
This wasn't a hosting experience, but when I first started renting rooms in my house, I was away for the first month. During that time, someone left the front door open and one lodger's bike was stolen. He blamed it on another lodger and demanded they pay for it. The other lodger was furious and refused. I had to do a bit of investigation and, it turned out that the guy whose bike was stolen was actually the last to come home so he was the one who left the door open.
At the same time, there was one couple who let a room for one month and then my friend was moving it. They demanded that the friend pay them the deposit back, even though of course, it had nothing to do with her.
More drama...
I have to wonder also, if you are getting mostly bookings from people who only need a one bedroom place, perhaps yours is too cheap. Have you looked at the prices of similar listings in your area? If it's not too cheap, then there's no problem really. You are getting the price of a two-bed, with less cleaning, laundry and wear and tear than if both bedrooms were occupied.