Absolutely put in your basement (lockable I presume) anything of monetary or sentimental value, alcohol, your clothes and personal possessions, food, bathroom items etc.
Anything you leave out can be stolen, damaged or used.
You can leave your clothes in locked wardrobes as long as you provide space for guest clothes and you have made this clear in your listing.
You absolutely cannot just rely on family, you need an experienced co-host to manage the listing on a day to day basis, manage your cleaner, quality check your place between bookings, ensure adequate supplies, dealing with any problem guests etc
Please make sure you have CCTV or similar to minimise the risk of guests bringing in additional guests they haven't paid for, partying etc.