@Kimberly853 I would take a breath because you are kind of co-mingling two types of issues...not washing his hands is not really your business, and washing something on 'heavy' is a completely minor issue. Major issues are allowing leaks, causing clogs, smoking, assuming you have made it clear there is no smoking on the property at all vs. only no smoking inside the house, and refusing to take out the trash as agreed.
After you take the breath and outline the real house rule issues, issues that are likely to cause expensive long term damage, then I would contact Airbnb and ask for a penalty free cancellation as @Debra300 suggests.
If you believe he will destroy your property out of vindictiveness, then make sure you and hopefully some other family/friends are on site when he leaves.
Expect a vindictive review. You might also start taking video or photos of any other evidence that he is not following the rules.
Don't expect common sense from guests, when they show it, feel thrilled, but assume that you have to treat them like 10 year olds.