@Kenia13,
The guest could contact Airbnb and ask for full refund (including Airbnb srvice costs) due to " extenuating circumstances":
https://www.airbnb.com/help/article/1339/how-do-i-file-an-extenuating-circumstances-claim
But then you will also not receive the cleaning fee...
Otherwise you can manually refund (the guest will loose Airbnb service fee anyway), but be sure the guest is not opting for the above mentioned at the same time.
You will be payed according the cancellation policy, so after that you can refund via resolution centre, keeping the cleaning fee.
Best regards,
Emiel