@Kate157
Why don't you leave both the large toothpaste AND toothbrush+paste pack (I think it should be 1 pack per person). I'm sure your guests will really appreciate the little considerations you provide to make their stay more comfortable~
The only reason I'm suggesting you leave both is personal - I usually like to travel with my own (electric) toothbrush, so when I see the toothbrush+paste pack I've always felt like it's a waste to open one of those just to use the toothpaste. I usually have toothpaste too, but travel tubes are small and I often forget to replace the one in my travel kit. On last-minute short 1~2 night trips there were a few times I forgot to pack my toothbrush and was really happy to see those little packs in the bathroom - they were a total lifesaver!
What I do in my listing is, I have the large tube of toothpaste visible on the bathroom counter and I mention that there are a few (usually 2, although I host only one guest at a time. my listing is a single occupancy private room) extra toothbrush+paste packs in the bathroom cabinet (next to where the hair dryer is) if they happen to need a toothbrush as well. I travel a lot for work and my company usually lets me book nice(r) hotels with good amenities so I've come into the habit of bringing these back home as back-up for guests. 🙂