@Andrew-And-Sue0 My suspicion is that your place is too large to attract weekday stays (where it is less likely large groups can get together). Do you have higher rates for weekends and lower rates mid week?
Also do you have a min stay of a week during the holidays?
Finally, if you make enough money from holidays and weekends perhaps you are better accepting less wear and tear on the property - If you price too low during the week you may end up with guests you don't want.