Make sure if you do list with separate listings that you do not put both the private rooms and the whole house on instant book. You could get simultaneous bookings, and then have to cancel one of them (and suffer the penalties). You can do either the individual rooms or the whole place. Then when some one books a room for a particular timeframe, you will need to manually block the whole place for the same time frame.
Alternatively, you could price the whole house for say 6 or 8 people, and then add a price per person, as the size of the group grows. This you could do with just one listing.